E-cigarette use among youth has quickly become the new epidemic our nation is facing. The adolescent brain is uniquely sensitive to the addictive nature of nicotine, potentially setting our youth up for a lifetime of nicotine addiction. Further exacerbating the problem is the multitude of enticing e-cigarette flavors, combined with targeted advertising to youth. For these reasons, it is not surprising that 1 in 4 youth report using e-cigarettes in the last month.